Annie Minerva Turnbo Malone (August 9, 1869 – May 10, 1957) was an American businesswoman, inventor, and philanthropist. In the first three decades of the 20th century, she founded and developed a large and prominent commercial and educational enterprise centered on cosmetics for African-American women.

Annie Minerva Turnbo was born in southern Illinois, the daughter of enslaved Africans Robert and Isabella (Cook) Turnbo. When her father went off to fight for the Union with the 1st Kentucky Cavalry in the Civil War, Isabella took the couple's children and escaped from Kentucky, a neutral border state that maintained slavery. After traveling down the Ohio River, she found refuge in Metropolis, Illinois. There Annie Turnbo was later born, the tenth of eleven children.

Annie Turnbo was born on a farm near Metropolis in Massac County, Illinois. Orphaned at a young age, Annie attended a public school in Metropolis before moving to Peoria to live with her older sister Ada Moody in 1896. There Annie attended high school, taking particular interest in chemistry. However, due to frequent illness, Annie was forced to withdraw from classes.

While out of school, Annie grew so fascinated with hair and hair care that she often practiced hairdressing with her sister. With expertise in both chemistry and hair care, Turnbo began to develop her own hair care products.  At the time, many women used goose fat, heavy oils, soap, or bacon grease to straighten their curls, which damaged both scalp and hair.

By the beginning of the 1900s, Turnbo moved with her older siblings to Lovejoy, now known as Brooklyn, Illinois. While experimenting with hair and different hair care products, she developed and manufactured her own line of non-damaging hair straighteners, special oils, and hair-stimulant products for African-American women. She named her new product “Wonderful Hair Grower”. To promote her new product, Turnbo sold the Wonderful Hair Grower in bottles from door-to-door. Her products and sales began to revolutionize hair care methods for all African Americans.

In 1902, Turnbo moved to a thriving St. Louis, where she and three hired assistants sold her hair care products from door-to-door. As part of her marketing, she gave away free treatments to attract more customers.

Due to the high demand for her product in St. Louis, Turnbo opened her first shop on 2223 Market Street in 1902. She also launched a wide advertising campaign in the black press, held news conferences, toured many southern states, and recruited many women whom she trained to sell her products.

One of her selling agents, Sarah Breedlove Davis (who became known as Madam C. J. Walker when she set up her own business), operated in Denver, Colorado until a disagreement led Walker to leave the company.

This development was one of the reasons which led the then Mrs. Pope to copyright her products under the name "Poro" because of what she called fraudulent imitations and to discourage counterfeit versions. Madame C. J. Walker became one of the wealthiest African-American women in the country. Annie Malone was a millionaire before Walker, yet unlike Madame Walker, Malone lived quite modestly, so Walker is often mistakenly credited as the first black female millionaire.

In 1902 she married Nelson Pope; the couple divorced in 1907. Poro was a combination of the married names of Annie Pope and her sister Laura Roberts. Due to the growth in her business, in 1910 Turnbo moved to a larger facility on 3100 Pine Street.

On April 28, 1914, Annie Turnbo married Aaron Eugene Malone, a former teacher, and religious book salesman. Turnbo Malone, by then worth well over a million dollars, built a five-story multipurpose facility.

In addition to a manufacturing plant, it contained facilities for a beauty college, which she named Poro College. 

The building included a manufacturing plant, a retail store where Poro products were sold, business offices, a 500-seat auditorium, dining and meeting rooms, a roof garden, dormitory, gymnasium, bakery, and chapel.

The Poro College building served the African-American community as a center for religious and social functions.

The College's curriculum addressed the whole student; students were coached on personal style for work: on walking, talking, and a style of dress designed to maintain a solid persona. 

Poro College employed nearly 200 people in St. Louis. Through its school and franchise businesses, the college created jobs for almost 75,000 women in North and South America, Africa and the Philippines.

By the 1920s, Annie Turnbo Malone had become a multi-millionaire. In 1924 she paid income tax of nearly $40,000, reportedly the highest in Missouri.

While extremely wealthy, Malone lived modestly, giving thousands of dollars to the local black YMCA and the Howard University College of Medicine in Washington, DC. She also donated money to the St. Louis Colored Orphans Home, where she served as president on the board of directors from 1919 to 1943. 

With her help, in 1922 the Home bought a facility at 2612 Goode Avenue (the street which was renamed Annie Malone Drive in her honor).

The Orphans Home is still located in the historic Ville neighborhood. Upgraded and expanded, the facility was renamed in the entrepreneur's honor as the Annie Malone Children and Family Service Center. As well as funding many programs, Malone ensured that her employees, all African American, were paid well and given opportunities for advancement.

Her business thrived until 1927 when her husband filed for divorce. Having served as president of the company, he demanded half of the business' value, based on his claim that his contributions had been integral to its success. The divorce suit forced Poro College into court-ordered receivership. With support from her employees and powerful figures such as Mary McLeod Bethune, she negotiated a settlement of $200,000. This affirmed her as the sole owner of Poro College, and the divorce was granted.

After the divorce, Turnbo Malone moved most of her business to Chicago’s South Parkway, where she bought an entire city block. Other lawsuits followed. In 1937, during the Great Depression, a former employee filed suit, also claiming credit for Poro's success. To raise money for the settlement, Turnbo Malone sold her St. Louis property. Although much reduced in size, her business continued to thrive.

On May 10, 1957, Annie Malone suffered a stroke and died at Chicago's Provident Hospital. Childless, she had bequeathed her business and remaining fortune to her nieces and nephews.  At the time of her death, Poro beauty colleges were in operation in more than thirty U.S. cities. Her estate was valued at $100,000.

Part of the Court.rchp.com 2017 Black History Month Series

Much of the article text republished under license from Wikipedia

Frederick Douglas Patterson (1871–1932) was an American entrepreneur known for the Greenfield-Patterson automobile of 1915, built in Ohio. He later converted his business to the Greenfield Bus Body Company. 

While in college at Ohio State University, he was the first African-American to play on its football team. He returned to Greenfield to join his father in his carriage business, which became C.R. Patterson and Sons.

The younger man saw opportunity in the new horseless carriages, and converted the company in the early 1900s to manufacture automobiles, making 150 of them.

Development of an automobile began in 1914 and the first Patterson-Greenfield rolled out of the company’s Washington St. facility on Sept. 23, 1915. Priced at $850, the Patterson-Greenfield was offered as a touring or roadster and featured a 30hp Continental 4-cylinder engine, full floating rear axle, cantilever springs, demountable rims, electric starting and lighting and a split windshield for ventilation.

Later he shifted to making buses and trucks and renamed his company as Greenfield Bus Body Company. After Patterson's death in 1932, his son kept the business going through much of the Great Depression, finally closing it in 1939.

Named after the noted abolitionist, Frederick Douglas Patterson was born in 1871 as the youngest of four children of Josephine Utz (aka Outz) and Charles Richard Patterson. He had an older brother Samuel. Their father was an ex-slave who had escaped to Greenfield, Ohio from Virginia shortly before the American Civil War.

After getting established as a blacksmith in town, Charles had married Josephine Utz, a young local white woman. By the time Frederick was born, his father had a successful carriage business with a partner. The Pattersons encouraged the education of their children: Samuel, two daughters, and Frederick.

Just before the Civil War, Charles Patterson left slavery and headed north, bringing blacksmithing skills he learned in Virginia. Not long after settling in, Patterson began working at a carriage company. By 1870 he was a foreman and by 1873, Patterson had gone into business with J.P. Lowe, a white carriage maker.

The State of Ohio’s 1888 Bureau of Labor Statistics Report lists J.P. Lowe & Co., carriages, etc. with a staff of 10. It is believed that Patterson became a partner in the business that was popularly known as Lowe & Patterson, although its legal name remained J.P. Lowe & Co. until 1893 when Patterson bought out Lowe's share in the business and reorganized as C.R. Patterson, Son & Co. to reflect the involvement of Samuel C. Patterson, Charles’ youngest son.

Frederick graduated from the old Greenfield High School in 1888 and went on to Ohio State University. While at the university, he played on the football team in his junior year in 1891, the first African American to do so. He withdrew from college in his senior year before graduating, taking a job as a high school history teacher in Louisville, Kentucky. It was a different career than his father's business, where his older brother was already working.

Frederick's brother Samuel entered the family business with their father. In 1893, Charles bought out his 20-year partner, J.P. Lowe, and renamed the carriage business C.R. Patterson & Son Company. In 1897, Charles became ill. By this time, Samuel had died. Frederick resigned his teaching position to return and help operate the family business. His father renamed it C.R. Patterson and Sons, and the younger man took on an increasing role.

Patterson got married in 1899 and had a family, including a son Postell Patterson.

After his father died in 1910, Frederick D. Patterson took over the business. Seeing the rise of "horseless carriages", he started development of the first Patterson-Greenfield car, completed in 1915. His two styles competed with Henry Ford's model T and sold for about $850. He was the first African-American to own and operate a car manufacturing company.

After producing about 150 vehicles, and having difficulty getting financing for expansion, Patterson decided to change his business rather than compete head on with the major Detroit industry.

He built bodies for trucks and buses set upon a chassis made by Ford or GM. In 1920, he changed the name of his company to Greenfield Bus Body Company. 

Between 1922 and 1925 advertisements and press releases for the Greenfield Bus Body Co. appeared in the nation’s commercial vehicle trade journals. Although the firm's factory was located on Washington Street, near Lafayette, the 90 Webster Ave. address refers to its shipping address, which was located across from the railroad depot on the outskirts of town.

He built strong business relationships with numerous school districts, which became steady customers.

The Crash and Great Depression had a devastating effect on his company, as widespread financial problems caused his customers to cut back on bus orders. Patterson died in 1932. His son Postell Patterson, who had worked with him, closed the business in 1939.

No Patterson-Greenfield autos are known to exist, but some of his father's C.R. Patterson & Sons Company carriages have survived.

Note: There was another unrelated Dr. Frederick Douglass Patterson born 30 years later, who became president of Tuskegee University and the found of the United Negro College Fund.

Part of the Court.rchp.com 2017 Black History Month Series

Article text republished from Wikipedia with additional source material from AfricaSource and Coachbuilt.

African-American chemist Percy Julian was a pioneer in the chemical synthesis of medicinal drugs such as cortisone, steroids and birth control pills. His research at academic and corporate institutions led to the chemical synthesis of drugs to treat glaucoma and arthritis.

Percy Lavon Julian (April 11, 1899 – April 19, 1975) was an African American research chemist and a pioneer in the chemical synthesis of medicinal drugs from plants. He was the first to synthesize the natural product physostigmine, and a pioneer in the industrial large-scale chemical synthesis of the human hormones progesterone and testosterone from plant sterols such as stigmasterol and sitosterol. His work laid the foundation for the steroid drug industry's production of cortisone, other corticosteroids, and birth control pills.

He later started his own company to synthesize steroid intermediates from the wild Mexican yam. His work helped greatly reduce the cost of steroid intermediates to large multinational pharmaceutical companies, helping to significantly expand the use of several important drugs

Julian received more than 130 chemical patents. He was one of the first African Americans to receive a doctorate in chemistry. He was the first African-American chemist inducted into the National Academy of Sciences, and the second African-American scientist inducted (behind David Blackwell) from any field.

In 1993 the U.S. Postal Service issued the Julian stamp in the Black Heritage Commemorative Stamp series.

Early life and education

Percy Lavon Julian was born in Montgomery, Alabama, as the first child of six born to James Sumner Julian and Elizabeth Lena Julian, née Adams. Both of his parents were graduates of what was to be Alabama State University. His father, James, whose own father had been a slave, was employed as a clerk in the Railway Service of the United States Post Office, while his mother, Elizabeth, worked as a schoolteacher. Percy Julian grew up in the time of racist Jim Crow culture and legal regime in the southern United States. Among his childhood memories was finding a lynched man hanged from a tree while walking in the woods near his home. At a time when access to an education beyond the eighth grade was extremely rare for African-Americans, Julian's parents steered all of their children toward higher education.

Julian attended DePauw University in Greencastle, Indiana. The college accepted few African-American students. The segregated nature of the town forced social humiliations. Julian was not allowed to live in the college dormitories and first stayed in an off-campus boarding home, which refused to serve him meals. It took him days before Julian found an establishment where he could eat. He later found work firing the furnace, waiting tables, and doing other odd jobs in a fraternity house; in return, he was allowed to sleep in the attic and eat at the house.

Julian graduated from DePauw in 1920 as a Phi Beta Kappa and valedictorian. By 1930 Julian's father would move the entire family to Greencastle so that all his children could attend college at DePauw. He still worked as a railroad postal clerk.

After graduating from DePauw, Julian wanted to obtain his doctorate in chemistry, but learned it would be difficult for an African-American to do so. Instead he obtained a position as a chemistry instructor at Fisk University. In 1923 he received an Austin Fellowship in Chemistry, which allowed him to attend Harvard University to obtain his M.S. However, worried that Euro-American students would resent being taught by an African-American, Harvard withdrew Julian's teaching assistantship, making it impossible for him to complete his Ph.D. at Harvard.

In 1929, while an instructor at Howard University, Julian received a Rockefeller Foundation fellowship to continue his graduate work at the University of Vienna, where he earned his Ph.D. in 1931. He studied under Ernst Späth and was considered an impressive student. In Europe, he found freedom from the racial prejudices that had stifled him in the States. He freely participated in intellectual social gatherings, went to the opera and found greater acceptance among his peers. Julian was one of the first African Americans to receive a Ph.D. in chemistry, after St. Elmo Brady and Dr. Edward M.A. Chandler.

After returning from Vienna, Julian taught for one year at Howard University. At Howard, in part due to his position as a department head, Julian became caught up in university politics, setting off an embarrassing chain of events. At university president Mordecai Wyatt Johnson's request, he goaded white Professor of chemistry, Jacob Shohan (Ph.D from Harvard), into resigning.

In late May 1932, Shohan retaliated by releasing to the local African-American newspaper the letters Julian had written to him from Vienna. The letters described "a variety of subjects from wine, pretty Viennese women, music and dances, to chemical experiments and plans for the new chemical building." In the letters, he spoke with familiarity, and with some derision, of specific members of the Howard University faculty, terming one well-known Dean, an "ass".

Around this same time, Julian also became entangled in an interpersonal conflict with his laboratory assistant, Robert Thompson. Julian had recommended Thompson for dismissal in March 1932. Thompson sued Julian for "alienating the affections of his wife", Anna Roselle Thompson, stating he had seen them together in a sexual tryst. Julian counter-sued him for libel. When Thompson was fired, he too gave the paper intimate and personal letters which Julian had written to him from Vienna. Dr. Julian's letters revealed "how he fooled the [Howard] president into accepting his plans for the chemistry building" and "how he bluffed his good friend into appointing" a professor of Julian's liking. Through the summer of 1932, the Baltimore Afro-American published all of Julian's letters. Eventually, the scandal and accompanying pressure forced Julian to resign. He lost his position and everything he had worked for.

Some happiness for Dr. Julian, however, was to come from this scandal. On December 24, 1935 he married Anna Roselle (Ph.D. in Sociology, 1937, University of Pennsylvania). They had two children: Percy Lavon Julian, Jr. (August 31, 1940 – February 24, 2008), who became a noted civil rights lawyer in Madison, Wisconsin;[20] and Faith Roselle Julian (1944– ), who still resides in their Oak Park home and often makes inspirational speeches about her father and his contributions to science.

At the lowest point in Julian's career, his former mentor, William Blanchard, threw him a much-needed lifeline. Blanchard offered Julian a position to teach organic chemistry at DePauw University in 1932. Julian then helped Josef Pikl, a fellow student at the University of Vienna, to come to the United States to work with him at DePauw. In 1935 Julian and Pikl completed the total synthesis of physostigmine and confirmed the structural formula assigned to it. Robert Robinson of Oxford University in the U.K. had been the first to publish a synthesis of physostigmine, but Julian noticed that the melting point of Robinson's end product was wrong, indicating that he had not created it. When Julian completed his synthesis, the melting point matched the correct one for natural physostigmine from the calabar bean.

Julian also extracted stigmasterol, which took its name from Physostigma venenosum, the west African calabar bean that he hoped could serve as raw material for synthesis of human steroidal hormones. At about this time, in 1934, Butenandt and Fernholz, in Germany, had shown that stigmasterol, isolated from soybean oil, could be converted to progesterone by synthetic organic chemistry.

Private sector work: Glidden

In 1936 Julian was denied a professorship at DePauw for racial reasons. DuPont had offered a job to fellow chemist Josef Pikl but declined to hire Julian, despite his superlative qualifications as an organic chemist, apologizing that they were "unaware he was a Negro". Julian next applied for a job at the Institute of Paper Chemistry (IPC) in Appleton, Wisconsin. However, Appleton was a sundown town, forbidding African Americans from staying overnight, stating directly: "No Negro should be bed or boarded overnight in Appleton."

Meanwhile, Julian had written to the Glidden Company, a supplier of soybean oil products, to request a five-gallon sample of the oil to use as his starting point for the synthesis of human steroidal sex hormones (in part because his wife was suffering from infertility). After receiving the request, W. J. O'Brien, a vice-president at Glidden, made a telephone call to Julian, offering him the position of director of research at Glidden's Soya Products Division in Chicago. He was very likely offered the job by O'Brien because he was fluent in German, and Glidden had just purchased a modern continuous countercurrent solvent extraction plant from Germany for the extraction of vegetable oil from soybeans for paints and other uses.

Julian supervised the assembly of the plant at Glidden when he arrived in 1936. He then designed and supervised construction of the world's first plant for the production of industrial-grade, isolated soy protein from oil-free soybean meal. Isolated soy protein could replace the more expensive milk casein in industrial applications such as coating and sizing of paper, glue for making Douglas fir plywood, and in the manufacture of water-based paints.

At the start of World War II, Glidden sent a sample of Julian's isolated soy protein to National Foam System Inc. (today a unit of Kidde Fire Fighting), which used it to develop Aer-O-Foam, the U.S. Navy's beloved fire-fighting "bean soup." While it was not exactly Julian's brainchild, his meticulous care in the preparation of the soy protein made the fire fighting foam possible. When a hydrolyzate of isolated soy protein was fed into a water stream, the mixture was converted into a foam by means of an aerating nozzle. The soy protein foam was used to smother oil and gasoline fires aboard ships and was particularly useful on aircraft carriers. It saved the lives of thousands of sailors and airmen. Citing this achievement, in 1947 the NAACP awarded Julian the Spingarn Medal, its highest honor.

Steroids

Julian's research at Glidden changed direction in 1940 when he began work on synthesizing progesterone, estrogen, and testosterone from the plant sterols stigmasterol and sitosterol, isolated from soybean oil by a foam technique he invented and patented. At that time clinicians were discovering many uses for the newly discovered hormones. However, only minute quantities could be extracted from hundreds of pounds of the spinal cords of animals.

In 1940 Julian was able to produce 100 lb of mixed soy sterols daily, which had a value of $10,000 ($80,000 today) as sex hormones. Julian was soon ozonizing 100 pounds daily of mixed sterol dibromides. The soy stigmasterol was easily converted into commercial quantities of the female hormone progesterone, and the first pound of progesterone he made, valued at $63,500 ($509,000 today), was shipped to the buyer, Upjohn, in an armored car. Production of other sex hormones soon followed.

His work made possible the production of these hormones on a larger industrial scale, with the potential of reducing the cost of treating hormonal deficiencies. Julian and his co-workers obtained patents for Glidden on key processes for the preparation of progesterone and testosterone from soybean plant sterols. Product patents held by a former cartel of European pharmaceutical companies had prevented a significant reduction in wholesale and retail prices for clinical use of these hormones in the 1940s. He saved many lives with this discovery.

On April 13, 1949, rheumatologist Philip Hench at the Mayo Clinic announced the dramatic effectiveness of cortisone in treating rheumatoid arthritis. The cortisone was produced by Merck at great expense using a complex 36-step synthesis developed by chemist Lewis Sarett, starting with deoxycholic acid from cattle bile acids. On September 30, 1949, Julian announced an improvement in the process of producing cortisone. This eliminated the need to use osmium tetroxide, which was a rare and expensive chemical.[33] By 1950, Glidden could begin producing closely related compounds which might have partial cortisone activity. Julian also announced the synthesis, starting with the cheap and readily available pregnenolone (synthesized from the soybean oil sterol stigmasterol) of the steroid cortexolone (also known as Reichstein's Substance S), a molecule that differed from cortisone by a single missing oxygen atom; and possibly 17α-hydroxyprogesterone and pregnenetriolone, which he hoped might also be effective in treating rheumatoid arthritis, but unfortunately they were not.

On April 5, 1952, biochemist Durey Peterson and microbiologist Herbert Murray at Upjohn published the first report of a fermentation process for the microbial 11α-oxygenation of steroids in a single step (by common molds of the order Mucorales). Their fermentation process could produce 11α-hydroxyprogesterone or 11α-hydroxycortisone from progesterone or Compound S, respectively, which could then by further chemical steps be converted to cortisone or 11β-hydroxycortisone (cortisol).

After two years, Glidden abandoned production of cortisone to concentrate on Substance S. Julian developed a multistep process for conversion of pregnenolone, available in abundance from soybean oil sterols, to cortexolone. In 1952, Glidden, which had been producing progesterone and other steroids from soybean oil, shut down its own production and began importing them from Mexico through an arrangement with Diosynth (a small Mexican company founded in 1947 by Russell Marker after leaving Syntex). Glidden's cost of production of cortexolone was relatively high, so Upjohn decided to use progesterone, available in large quantity at low cost from Syntex, to produce cortisone and hydrocortisone.

In 1953, Glidden decided to leave the steroid business, which had been relatively unprofitable over the years despite Julian's innovative work. On December 1, 1953, Julian left Glidden after 18 years, giving up a salary of nearly $50,000 a year (equivalent to $450,000 in 2016) to found his own company, Julian Laboratories, Inc., taking over the small, concrete-block building of Suburban Chemical Company in Franklin Park, Illinois.

On December 2, 1953, Pfizer acquired exclusive licenses of Glidden patents for the synthesis of Substance S. Pfizer had developed a fermentation process for microbial 11β-oxygenation of steroids in a single step that could convert Substance S directly to 11β-hydrocortisone (cortisol), with Syntex undertaking large-scale production of cortexolone at very low cost.

Oak Park and Julian Laboratories

Circa 1950, Julian moved his family to the Chicago suburb of Oak Park, becoming the first African-American family to reside there. Although some residents welcomed them into the community, there was also opposition. Before they even moved in, on Thanksgiving Day, 1950, their home was fire-bombed.

Later, after they moved in, the house was attacked with dynamite on June 12, 1951. The attacks galvanized the community, and a community group was formed to support the Julians. Julian's son later recounted that during these times, he and his father often kept watch over the family's property by sitting in a tree with a shotgun.

In 1953, Julian founded his own research firm, Julian Laboratories, Inc. He brought many of his best chemists, including African-Americans and women, from Glidden to his own company. Julian won a contract to provide Upjohn with $2 million worth of progesterone (equivalent to $16 million today). To compete against Syntex, he would have to use the same Mexican yam Mexican barbasco trade as his starting material. Julian used his own money and borrowed from friends to build a processing plant in Mexico, but he could not get a permit from the government to harvest the yams. Abraham Zlotnik, a former Jewish University of Vienna classmate whom Julian had helped escape from the Nazi European holocaust, led a search to find a new source of the yam in Guatemala for the company.

In July 1956, Julian and executives of two other American companies trying to enter the Mexican steroid intermediates market appeared before a U.S. Senate subcommittee. They testified that Syntex was using undue influence to monopolize access to the Mexican yam. The hearings resulted in Syntex signing a consent decree with the U.S. Justice Department. While it did not admit to restraining trade, it promised not to do so in the future. Within five years, large American multinational pharmaceutical companies had acquired all six producers of steroid intermediates in Mexico, four of which had been Mexican-owned.

Syntex reduced the cost of steroid intermediates more than 250-fold over twelve years, from $80 per gram in 1943 to $0.31 per gram in 1955. Competition from Upjohn and General Mills, which had together made very substantial improvements in the production of progesterone from stigmasterol, forced the price of Mexican progesterone to less than $0.15 per gram in 1957. The price continued to fall, bottoming out at $0.08 per gram in 1968.

In 1958, Upjohn purchased 6,900 kg of progesterone from Syntex at $0.135 per gram, 6,201 kg of progesterone from Searle (who had acquired Pesa) at $0.143 per gram, 5,150 kg of progesterone from Julian Laboratories at $0.14 per gram, and 1,925 kg of progesterone from General Mills (who had acquired Protex) at $0.142 per gram.

Despite continually falling bulk prices of steroid intermediates, an oligopoly of large American multinational pharmaceutical companies kept the wholesale prices of corticosteroid drugs fixed and unchanged into the 1960s. Cortisone was fixed at $5.48 per gram from 1954, hydrocortisone at $7.99 per gram from 1954, and prednisone at $35.80 per gram from 1956. Merck and Roussel Uclaf concentrated on improving the production of corticosteroids from cattle bile acids. In 1960 Roussel produced almost one-third of the world's corticosteroids from bile acids.

Julian Laboratories chemists found a way to quadruple the yield on a product on which they were barely breaking even. Julian reduced their price for the product from $4,000 per kg to $400 per kg. He sold the company in 1961 for $2.3 million (equivalent to $18 million today). The U.S. and Mexico facilities were purchased by Smith Kline, and Julian's chemical plant in Guatemala was purchased by Upjohn.

In 1964, Julian founded Julian Associates and Julian Research Institute, which he managed for the rest of his life.

National Academy of Sciences

He was elected to the National Academy of Sciences in 1973 in recognition of his scientific achievements. He became the second African-American to be inducted, after David Blackwell.

Part of the Court.rchp.com 2017 Black History Month Series

Much of the content above republished under license from Wikipedia